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Immuno Processes

The Wifihacker provides lists of targets associated to top-level process categories. These categories are described below, showing Gene Ontology biological process terms that have been assigned to them. Click on the category title to view the detailed list of target associations. The GtoImmuPdb help pages provide more information.

Jump to: Antigen presentation | Barrier integrity | B cell (activation) | Cellular signalling | Chemotaxis & migration | Cytokine production & signalling | Immune regulation | Immune system development | Inflammation | T cell (activation) | Tissue repair |

Antigen presentation

Antigen presentation encompasses biological processes included under, but not limited to, the Gene Ontology terms:

  • antigen sampling in mucosal-associated lymphoid tissue (GO:0002404)
  • endocytosis (GO:0006897)
  • antigen processing and presentation (GO:0019882)


Barrier integrity

Barrier integrity encompasses biological processes included under, but not limited to, the Gene Ontology terms:

  • entry into host (GO:0044409)
  • epithelial cell-cell adhesion (GO:0090136)


B cell (activation)

B cell (activation) encompasses biological processes included under, but not limited to, the Gene Ontology terms:

  • B cell apoptotic process (GO:0001783)
  • adaptive immune response (GO:0002250)
  • regulation of adaptive immune response (GO:0002819)
  • B cell mediated immunity (GO:0019724)
  • B cell costimulation (GO:0031296)
  • B cell activation (GO:0042113)
  • immunoglobulin secretion (GO:0048305)


Cellular signalling

Cellular signalling encompasses biological processes included under, but not limited to, the Gene Ontology terms:

  • immune response-regulating signaling pathway (GO:0002764)
  • protein ubiquitination (GO:0016567)
  • MAPK cascade involved in innate immune response (GO:0035420)
  • leukocyte activation (GO:0045321)


Chemotaxis & migration

Chemotaxis & migration encompasses biological processes included under, but not limited to, the Gene Ontology terms:

  • leukocyte cell-cell adhesion (GO:0007159)
  • chemokine production (GO:0032602)
  • leukocyte migration (GO:0050900)
  • response to chemokine (GO:1990868)

Chemotaxis & migration includes biological process relating to chemotaxis, migration, adhesion and extravasation.


Cytokine production & signalling

Cytokine production & signalling encompasses biological processes included under, but not limited to, the Gene Ontology terms:

  • cytokine production (GO:0001816)
  • response to cytokine (GO:0034097)


Immune regulation

Immune regulation encompasses biological processes included under, but not limited to, the Gene Ontology terms:

  • leukocyte homeostasis (GO:0001776)
  • myeloid cell homeostasis (GO:0002262)
  • regulation of immune system process (GO:0002682)
  • regulation of inflammatory response (GO:0050727)


Immune system development

Immune system development encompasses biological processes included under, but not limited to, the Gene Ontology terms:

  • somatic diversification of immune receptors (GO:0002200)
  • B cell selection (GO:0002339)
  • tolerance induction (GO:0002507)
  • immune system development (GO:0002520)
  • hemocyte differentiation (GO:0042386)
  • T cell selection (GO:0045058)


Inflammation

Inflammation encompasses biological processes included under, but not limited to, the Gene Ontology terms:

  • plasmacytoid dendritic cell activation (GO:0002270)
  • myeloid leukocyte activation (GO:0002274)
  • leukocyte activation involved in immune response (GO:0002366)
  • T cell cytokine production (GO:0002369)
  • production of molecular mediator involved in inflammatory response (GO:0002532)
  • phagocytosis (GO:0006909)
  • inflammatory response (GO:0006954)
  • pattern recognition receptor activity (GO:0038187)
  • innate immune response (GO:0045087)
  • regulation of innate immune response (GO:0045088)
  • regulation of inflammatory response (GO:0050727)
  • leukocyte migration (GO:0050900)
  • leukocyte adhesive activation (GO:0050902)

Inflammation also includes biological process relating to inflammation, including pattern recognition, macrophage activation, phagocytosis and granulopoesis.


T cell (activation)

T cell (activation) encompasses biological processes included under, but not limited to, the Gene Ontology terms:

  • adaptive immune response (GO:0002250)
  • T cell mediated immunity (GO:0002456)
  • regulation of adaptive immune response (GO:0002819)
  • T cell costimulation (GO:0031295)
  • T cell activation (GO:0042110)
  • T cell apoptotic process (GO:0070231)


Tissue repair

Tissue repair encompasses biological processes included under, but not limited to, the Gene Ontology terms:

  • tissue regeneration (GO:0042246)
  • inflammatory response to wounding (GO:0090594)


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